Thursday, June 26, 2014

Ask Well: Fatty Liver and Diet



By ANAHAD O'CONNOR from NYT Health http://ift.tt/1sJrfj5

Politicians’ Prescriptions for Marijuana Defy Doctors and Data



By CATHERINE SAINT LOUIS from NYT Health http://ift.tt/1pFzBCO

For Elderly Patients, a Sharper Focus



By PAULA SPAN from NYT Health http://ift.tt/1mxQd0l

Supplements Found to Ease Gestational Diabetes



By NICHOLAS BAKALAR from NYT Health http://ift.tt/1nI6qh2

Living With Cancer: The New Medicine



By SUSAN GUBAR from NYT Health http://ift.tt/1nLbwYE

Monday, June 23, 2014

Mediterranean Cucumber and Yogurt Salad With Red or Black Quinoa



By MARTHA ROSE SHULMAN from NYT Health http://ift.tt/1pwKkQ3

Green Bean Salad With Lime Vinaigrette and Red Quinoa



By MARTHA ROSE SHULMAN from NYT Health http://ift.tt/1pwKkPR

Warning Unheeded, Heart Drugs Are Recalled



By KATIE THOMAS from NYT Health http://ift.tt/1uZfTn1

Where Recovery Is Rare



By GINA KOLATA from NYT Health http://ift.tt/1wp5IL1

Herpes Infected ‘Since Before We Were Human’



By DOUGLAS QUENQUA from NYT Health http://ift.tt/1pvKbwf

Good Night, Margaret



By Rick Gershon and Catherine Spangler from NYT Health http://ift.tt/1m79ukb

Vitamin D Screening Not Backed by Expert Panel



By ANAHAD O'CONNOR from NYT Health http://ift.tt/1iqYFPi

I Had Alice in Wonderland Syndrome



By HELENE STAPINSKI from NYT Health http://ift.tt/1woMsNQ

Cool at 13, Adrift at 23



By JAN HOFFMAN from NYT Health http://ift.tt/1pvqODi

Red Quinoa Salad With Walnuts, Asparagus and Dukkah



By MARTHA ROSE SHULMAN from NYT Health http://ift.tt/1uXTZ3w

Chickpea, Quinoa and Celery Salad With Middle Eastern Flavors



By MARTHA ROSE SHULMAN from NYT Health http://ift.tt/1iqdzFD

Spicy Quinoa Salad With Broccoli, Cilantro and Lime



By MARTHA ROSE SHULMAN from NYT Health http://ift.tt/1qEPlcU

Cleaner Air Linked to Fewer Deaths



By NICHOLAS BAKALAR from NYT Health http://ift.tt/1wnyHPn

Friday, June 20, 2014

Broccoli, Stems and All



By MARTHA ROSE SHULMAN from NYT Health http://ift.tt/1ysHVvG

Issue Highlights

Michael Chin Worcester

Lee et al In this unique edition of our “Around the Globe” series, Anne Lee and colleagues describe their experiences working in both Shenzhen in mainland China and in Hong Kong. These are two geographically adjacent cities in southern China, but the government and health care systems are strikingly different. One is rooted in the communist past but now rapidly expanding and evolving. The other is rooted in a British colonial past with strong ties to a western medical culture. This beautifully written piece boldly contrasts the two and looks forward to a future of mutual cooperation and benefit.


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Oncology Scan—Novel Treatment Strategies for Gastrointestinal Cancers

Michael Chin Worcester

This edition of the Oncology Scan is the first with a new Gastrointestinal (GI) Editorial Team in place. We would first like to acknowledge Dr Brian Czito, who, after 2 years of fantastic service as one of the original associate editors, rotates out of the group. We also acknowledge the other outstanding members of our original group, Drs Jeffrey Meyer and Jennifer Wo, who are continuing on as associate editors. We welcome to our group Drs Stanley Liauw, Thomas Brunner, and Jason Chia-Hsien Cheng as new associate editors. For several years, they have been outstanding reviewers for this journal, and we are excited to have them join the editorial board. They each bring their own set of clinical and academic expertise in the field of GI cancers, and we look forward to working with them.


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A Tale of Two Cities in China: Hong Kong and Shenzhen

Michael Chin Worcester

Hong Kong and Shenzhen are 2 geographically adjacent cities in southern China, but the government systems (including health care systems) are strikingly different. This is a vivid example of the “One Country—Two Systems” principle so innovatively promulgated by the late Xiaoping Deng.


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Radiogenomics: Radiobiology Enters the Era of Big Data and Team Science

Michael Chin Worcester

Radiogenomics is the study of the link between germ line genotypic variations and the large clinical variability observed in response to radiation therapy. The radiogenomics hypothesis is that a proportion of the variance in the phenotype of interest—radiation toxicity—is explained by genotypic variation. Thus, the aim of radiogenomics is to identify the alleles that underlie the inherited dissimilarities in phenotype. However, this hypothesis does not assume that all of the phenotypic differences are due to germ line genetic alterations, but it acknowledges that epigenetic changes (inherited and acquired) and other factors could also be important.


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Cost-Effectiveness in Radiation Oncology: An Uncomfortable but Necessary Question

Michael Chin Worcester

The impact of expensive medical technology on increasing healthcare costs in the United States rightfully draws attention from consumers and policymakers alike. Radiation oncology—a medical specialty intricately entwined with costly technology—has recently attracted substantial scrutiny for costly treatments with disputed benefit. The high cost of technology inherent to radiation oncology naturally leads to the question of cost-effectiveness.


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Bone Marrow–Derived Stromal Cell Therapy in Cirrhosis: Clinical Evidence, Cellular Mechanisms, and Implications for the Treatment of Hepatocellular Carcinoma

Michael Chin Worcester

Current treatment options for hepatocellular carcinoma (HCC) are often limited by the presence of underlying liver disease. In patients with liver cirrhosis, surgery, chemotherapy, and radiation therapy all carry a high risk of hepatic complications, ranging from ascites to fulminant liver failure. For patients receiving radiation therapy, cirrhosis dramatically reduces the already limited radiation tolerance of the liver and represents the most important clinical risk factor for the development of radiation-induced liver disease. Although improvements in conformal radiation delivery techniques have improved our ability to safely irradiate confined areas of the liver to increasingly higher doses with excellent local disease control, patients with moderate-to-severe liver cirrhosis continue to face a shortage of treatment options for HCC. In recent years, evidence has emerged supporting the use of bone marrow–derived stromal cells (BMSCs) as a promising treatment for liver cirrhosis, with several clinical studies demonstrating sustained improvement in clinical parameters of liver function after autologous BMSC infusion. Three predominant populations of BMSCs, namely hematopoietic stem cells, mesenchymal stem cells, and endothelial progenitor cells, seem to have therapeutic potential in liver injury and cirrhosis. Preclinical studies of BMSC transplantation have identified a range of mechanisms through which these cells mediate their therapeutic effects, including hepatocyte transdifferentiation and fusion, paracrine stimulation of hepatocyte proliferation, inhibition of activated hepatic stellate cells, enhancement of fibrolytic matrix metalloproteinase activity, and neovascularization of regenerating liver. By bolstering liver function in patients with underlying Child’s B or C cirrhosis, autologous BMSC infusion holds great promise as a therapy to improve the safety, efficacy, and utility of surgery, chemotherapy, and hepatic radiation therapy in the treatment of HCC.


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Thursday, June 19, 2014

Dr. Lorna Wing, Who Broadened Views of Autism, Dies at 85



By PAUL VITELLO from NYT Health http://ift.tt/USIGit

Up to 75 C.D.C. Scientists May Have Been Exposed to Anthrax



By SABRINA TAVERNISE from NYT Health http://ift.tt/1yppLuH

The Weekly Health Quiz



By from NYT Health http://ift.tt/1m0NNXV

Game On, Weekend Warrior



By Krishnan Vasudevan from NYT Health http://ift.tt/1iM31Ly

Ask Well: Weekend Warriors



By GRETCHEN REYNOLDS from NYT Health http://ift.tt/1iM5A06

Obama to Address Nation on Iraq Crisis by PETER BAKER

Michael Chin Worcester



By PETER BAKER


President Obama, who has been facing pressure to intervene, will make a televised statement on the situation in Iraq, where Sunni militants have captured several cities.


Published: June 20, 2014 at 4:00AM


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How Do You Take the Measure of a School Year? by JESSICA LAHEY

Michael Chin Worcester



By JESSICA LAHEY


Was the 2013-14 school year, with its Common Core, its policy debates and its snow days, a success for education, for schools, or for students?


Published: June 19, 2014 at 4:00AM


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